Package: gJLS2
Title: A Generalized Joint Location and Scale Framework for Association
        Testing
Version: 0.3.1
Authors@R: 
    c(person(given = "Wei",
           family = "Deng",
           role = c("aut", "cre"),
           email = "dengwq@mcmaster.ca"),
     person(given = "Lei",
           family = "Sun",
           role = c("aut"),
           email = "lei.sun@utoronto.ca"))          
Description: An update to the Joint Location-Scale (JLS) testing
        framework that identifies associated SNPs, gene-sets and
        pathways with main and/or interaction effects on quantitative
        traits (Soave et al., 2015; <doi:10.1016/j.ajhg.2015.05.015>).
        The JLS method simultaneously tests the null hypothesis of
        equal mean and equal variance across genotypes, by aggregating
        association evidence from the individual location/mean-only and
        scale/variance-only tests using Fisher's method. The
        generalized joint location-scale (gJLS) framework has been
        developed to deal specifically with sample correlation and
        group uncertainty (Soave and Sun, 2017;
        <doi:10.1111/biom.12651>). The current release: gJLS2, include
        additional functionalities that enable analyses of X-chromosome
        genotype data through novel methods for location (Chen et al.,
        2021; <doi:10.1002/gepi.22422>) and scale (Deng et al., 2019;
        <doi:10.1002/gepi.22247>).
License: GPL-3 + file LICENSE
Encoding: UTF-8
LazyData: true
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.1.1
Suggests: knitr, markdown, ggplot2, moments, MASS, MCMCpack
VignetteBuilder: knitr
Imports: methods, nlme, quantreg, parallel, plyr
Depends: R (>= 3.6.0)
Repository: https://weiakanedeng.r-universe.dev
Date/Publication: 2022-10-07 23:31:10 UTC
RemoteUrl: https://github.com/weiakanedeng/gjls2
RemoteRef: HEAD
RemoteSha: a07b78ca326debabf6d51978f26f571a772a69b6
NeedsCompilation: no
Packaged: 2026-07-14 08:38:52 UTC; root
Author: Wei Deng [aut, cre],
  Lei Sun [aut]
Maintainer: Wei Deng <dengwq@mcmaster.ca>